Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ticam1tm1Aki
Name:	TIR domain containing adaptor molecule 1; targeted mutation 1, Shizuo Akira
MGI ID:	MGI:3029019
Synonyms:	Ticam1-, TRIF-
Gene:	Ticam1  Location: Chr17:56576462-56583767 bp, - strand  Genetic Position: Chr17, 29.24 cM
Alliance:	Ticam1tm1Aki page

Germline Transmission:	Earliest citation of germline transmission: J:84679
Parent Cell Line:	E14.1 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The entire exon of this single-exon locus was replaced with a neomycin resistance gene cassette inserted by homologous recombination. (J:84679)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ticam1 Mutation:	53 strains or lines available

Original:	J:84679 Yamamoto M, et al., Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway. Science. 2003 Aug 1;301(5633):640-3
All:	276 reference(s)