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Gene Expression Data
Assay Details
Assay
Reference: J:87163 Zhang Z, et al., Msx1/Bmp4 genetic pathway regulates mammalian alveolar bone formation via induction of Dlx5 and Cbfa1. Mech Dev. 2003 Dec;120(12):1469-79
Assay type: RNA in situ
MGI Accession ID: MGI:3028935
Gene symbol: Runx2
Gene name: runt related transcription factor 2
Probe: Cbfa1 probe1
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen Cbfa-1 E14.5: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lower jaw molar mesenchyme Present Uniform 2E Expression is in the dental papilla and the dental follicle.
TS22: upper jaw molar mesenchyme Present Uniform 2E Expression is in the dental papilla and the dental follicle.
TS22: lower jaw skeleton Present Regionally restricted 2E Expression is in the alveolar bone.
TS22: upper jaw skeleton Present Regionally restricted 2E Expression is in the alveolar bone.
Specimen Cbfa-1 E16.5: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: lower jaw molar mesenchyme Present Uniform 2F Expression is in the dental papilla and the dental follicle.
TS24: upper jaw molar mesenchyme Present Uniform 2F Expression is in the dental papilla and the dental follicle.
TS24: lower jaw skeleton Present Regionally restricted 2F Expression is in the alveolar bone.
TS24: upper jaw skeleton Present Regionally restricted 2F Expression is in the alveolar bone.
Specimen Cbfa1 Wt: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: Meckel's cartilage Present 3A
TS21: lower jaw molar mesenchyme Present 3A
Specimen Cbfa1 Msx1 -/-: embryonic day 13.5; Msx1tm1Rilm/Msx1tm1Rilm (more )
Structure Level Pattern Image Note
TS21: lower jaw molar mesenchyme Absent 3B
TS21: Meckel's cartilage Present 3B
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
MGI 6.23 		The Jackson Laboratory