Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Fgf8tm1Moon
Name:	fibroblast growth factor 8; targeted mutation 1, Anne M Moon
MGI ID:	MGI:2686864
Synonyms:	Fgf8GFP
Gene:	Fgf8  Location: Chr19:45725237-45731354 bp, - strand  Genetic Position: Chr19, 38.75 cM, cytoband C3-D
Alliance:	Fgf8tm1Moon page

Germline Transmission:	Earliest citation of germline transmission: J:87304
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: Exon 5 was flanked by single loxP sites inserted by homologous recombination. Sequence encoding GFP was included downstream of the second loxP site, such that after cre-mediated recombination, GFP will be under the control of the Fgf8 gene. (J:87304)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	5 assay results
In Structures Affected by this Mutation:	16 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Fgf8 Mutation:	18 strains or lines available

Original:	J:87304 Macatee TL, et al., Ablation of specific expression domains reveals discrete functions of ectoderm- and endoderm-derived FGF8 during cardiovascular and pharyngeal development. Development. 2003 Dec;130(25):6361-74
All:	12 reference(s)