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Gene Expression Data
Assay Details
Assay
Reference: J:56430 Wyatt S, et al., Selective regulation of trkC expression by NT3 in the developing peripheral nervous system. J Neurosci. 1999 Aug 1;19(15):6559-70
Assay type: RT-PCR
MGI Accession ID: MGI:2684769
Gene symbol: Ntrk3
Gene name: neurotrophic tyrosine kinase, receptor, type 3
Probe: trkC-pA, trkC-pB
Assay notes: Primer set amplifies all trkC transcripts. Levels of transcripts lacking the tyrosine kinase domain (TK-) were calculated by subtracting TK+ levels (assayed using primers trkC-pA and trkC-pB; see assay MGI:2684751) from total trkC levels.
Results
 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Amount Genetic BackgroundMutant Allele(s)Sex
E11 NT3+/+ E11.0 (a) TS18: trigeminal ganglion Present Not Specified involves: 129S4/SvJae * BALB/c Not Specified
E12 NT3+/+ E12.0 (a) TS20: trigeminal ganglion Present Not Specified involves: 129S4/SvJae * BALB/c Not Specified
E13 NT3+/+ E13.0 (a) TS21: trigeminal ganglion Present Not Specified involves: 129S4/SvJae * BALB/c Not Specified
E14 NT3+/+ E14.0 (a) TS22: trigeminal ganglion Present Not Specified involves: 129S4/SvJae * BALB/c Not Specified
E15 NT3+/+ E15.0 (a) TS23: trigeminal ganglion Present Not Specified involves: 129S4/SvJae * BALB/c Not Specified
E16 NT3+/+ E16.0 (a) TS24: trigeminal ganglion Present Not Specified involves: 129S4/SvJae * BALB/c Not Specified
E18 NT3+/+ E18.0 (a) TS26: trigeminal ganglion Present Not Specified involves: 129S4/SvJae * BALB/c Not Specified
E11 NT3-/- E11.0 (a) TS18: trigeminal ganglion Present (b) Not Specified involves: 129S4/SvJae * BALB/c Ntf3tm1Jae/Ntf3tm1JaeNot Specified
E12 NT3-/- E12.0 (a) TS20: trigeminal ganglion Present (b) Not Specified involves: 129S4/SvJae * BALB/c Ntf3tm1Jae/Ntf3tm1JaeNot Specified
E13 NT3-/- E13.0 (a) TS21: trigeminal ganglion Present (c) Not Specified involves: 129S4/SvJae * BALB/c Ntf3tm1Jae/Ntf3tm1JaeNot Specified
E14 NT3-/- E14.0 (a) TS22: trigeminal ganglion Present (c) Not Specified involves: 129S4/SvJae * BALB/c Ntf3tm1Jae/Ntf3tm1JaeNot Specified
E15 NT3-/- E15.0 (a) TS23: trigeminal ganglion Present (c) Not Specified involves: 129S4/SvJae * BALB/c Ntf3tm1Jae/Ntf3tm1JaeNot Specified
E16 NT3-/- E16.0 (a) TS24: trigeminal ganglion Present (c) Not Specified involves: 129S4/SvJae * BALB/c Ntf3tm1Jae/Ntf3tm1JaeNot Specified
E18 NT3-/- E18.0 (a) TS26: trigeminal ganglion Present (c) Not Specified involves: 129S4/SvJae * BALB/c Ntf3tm1Jae/Ntf3tm1JaeNot Specified
Notes:
(a) Age of embryo at noon of plug day not specified in reference. Authors state the precise stage of development was determined by the criteria of Theiler (1972).
(b) No significant differences between wild-type and NT3-/- embryos at E11 and E12.
(c) Marked decrease by E13, maintained throughout subsequent development.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory