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Gene Expression Data
Assay Details
Assay
Reference: J:15224 Veis DJ, et al., Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair. Cell. 1993 Oct 22;75(2):229-40
Assay type: Western blot
MGI Accession ID: MGI:2682805
Gene symbol: Bcl2
Gene name: B cell leukemia/lymphoma 2
Antibody: 3F11
Detection system: Secondary antibody coupled to horseradish peroxidase
Results Image: 2
 Sample Information Bands Other Sample Information
Lane AgeStructure 25 kDa Genetic BackgroundMutant Allele(s)Sex
-/+ spleen P w 2 TS28: spleen Present (a) involves: 129S2/SvPas * C57BL/6 Bcl2tm1Sjk/Bcl2+Not Specified
-/- spleen P w 2 TS28: spleen Absent involves: 129S2/SvPas * C57BL/6 Bcl2tm1Sjk/Bcl2tm1SjkNot Specified
+/+ spleen P w 2 TS28: spleen Present Not Specified Not Specified
-/+ thymus P w 2 TS28: thymus Present (a) involves: 129S2/SvPas * C57BL/6 Bcl2tm1Sjk/Bcl2+Not Specified
-/- thymus P w 2 TS28: thymus Absent involves: 129S2/SvPas * C57BL/6 Bcl2tm1Sjk/Bcl2tm1SjkNot Specified
+/+ thymus P w 2 TS28: thymus Present Not Specified Not Specified
-/+ cerebellum P w 2 TS28: cerebellum Present (a) involves: 129S2/SvPas * C57BL/6 Bcl2tm1Sjk/Bcl2+Not Specified
-/- cerebellum P w 2 TS28: cerebellum Absent involves: 129S2/SvPas * C57BL/6 Bcl2tm1Sjk/Bcl2tm1SjkNot Specified
+/+ cerebellum P w 2 TS28: cerebellum Present Not Specified Not Specified
+/+ E15 head E15.0 (b) TS23: head Present Not Specified Not Specified
-/+ E15 head E15.0 (b) TS23: head Present (a) involves: 129S2/SvPas * C57BL/6 Bcl2tm1Sjk/Bcl2+Not Specified
-/- E15 head E15.0 (b) TS23: head Absent involves: 129S2/SvPas * C57BL/6 Bcl2tm1Sjk/Bcl2tm1SjkNot Specified
Notes:
(a) Expression levels in heterozygotes are lower than those seen in wild-type animals.
(b) Age of embryo at noon of plug day not specified in reference.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory