Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Gabrg2tm2Lusc
Name:	gamma-aminobutyric acid type A receptor, subunit gamma 2; targeted mutation 2, Bernhard Luscher
MGI ID:	MGI:2680624
Synonyms:	fgamma2
Gene:	Gabrg2  Location: Chr11:41801030-41891684 bp, - strand  Genetic Position: Chr11, 24.8 cM
Alliance:	Gabrg2tm2Lusc page

Germline Transmission:	Earliest citation of germline transmission: J:86221
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: Exon 8 was left flanked by single loxP sites after an frt flanked neo cassette was excised via Flp-mediated recombination. A single flp site was left immediately downstream of the 3' loxP site. (J:86221)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gabrg2 Mutation:	41 strains or lines available

Original:	J:86221 Schweizer C, et al., The gamma2 subunit of GABA(A) receptors is required for maintenance of receptors at mature synapses. Mol Cell Neurosci. 2003 Oct;24(2):442-50
All:	15 reference(s)