Summary | Transgene origin | Transgene description | Phenotypes | Disease models | Tumor data | Find Mice (IMSR) | References

Symbol:	Tg(SFTPC-rtTA)5Jaw
Name:	transgene insertion 5, Jeffrey A Whitsett
MGI ID:	MGI:2445716
Synonyms:	hSPC-rtTA+, SFTPC-rtTA, Sp-c-rtta, SP-CrtTA, SPC-rtTA, SP-C-rtTA mice (Line 1), SP-C-rtTAtg, SP-CrtTAtg, Tg(SFTPC-rtTA)1Jaw
Transgene:	Tg(SFTPC-rtTA)5Jaw  Location: unknown
Alliance:	Tg(SFTPC-rtTA)5Jaw page

Strain of Origin:

Not Specified

Transgene Type:    Transgenic (Transactivator) Mutation:    Insertion   Mutation details: The transgene is composed of 3.7 kb of human SFTPC promoter, a reverse tetracycline responsive transactivator gene (rt-TA), and a 0.45 kb SV40 polyadenylation signal. Transgene expression was confirmed by RT-PCR analysis. The human SFTPC promoter is active in respiratory epithelial cells. (J:61736)

View phenotypes and curated references for all genotypes (concatenated display).

List all tumor models in MMHCdb carrying Tg(SFTPC-rtTA)5Jaw

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 4 strains available      Cell Lines: 0 lines available

Original:	J:61736 Tichelaar JW, et al., Conditional expression of fibroblast growth factor-7 in the developing and mature lung. J Biol Chem. 2000 Apr 21;275(16):11858-64
All:	172 reference(s)