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Gene Expression Data
Assay Details
Assay
Reference: J:85509 Ferguson JW, et al., Developmental expression patterns of Beta-ig (betaIG-H3) and its function as a cell adhesion protein. Mech Dev. 2003 Aug;120(8):851-64
Assay type: RNA in situ
MGI Accession ID: MGI:2677513
Gene symbol: Tgfbi
Gene name: transforming growth factor, beta induced
Probe: Beta-ig cDNA
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 2: A,C: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: vertebral cartilage condensation Present 2A

Specimen 2: D,F: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: rib pre-cartilage condensation Present 2D

Specimen 2: G,I: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: humerus cartilage condensation Present 2G

Specimen 2: J,L: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: nasal septum mesenchyme Present Regionally restricted 2J Expression is in the nasal cartilage primordia.

Specimen 3: A,C: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cranium Present Regionally restricted 3A Expression is in the growth plates.

Specimen 3: D,F: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: vertebral cartilage condensation Present Regionally restricted 3D Expression is in the growth plates.

Specimen 4: A,C: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: scapula Present Regionally restricted 4A Expression is in interior chondrocytes.

Specimen 4: D,F: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: tibia Present Regionally restricted 4D Expression is in regions of endochondrial ossification initiation.

Specimen 4: G,I: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: temporal bone Present Regionally restricted 4G Expression is in the intramembraneous ossification region.
TS25: brain Absent 4G

Specimen 4: J,L: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: spinal cord dura mater Present Regionally restricted 4J Expression is in regions of proliferating chondrocytes, whereas little if any expression was seen in areas with apparent hypertrophic chondrocytes.
TS25: spinal cord floor plate Absent 4J
TS25: spinal cord lateral wall Absent 4J
TS25: spinal cord roof plate Absent 4J

Specimen 5: A,C: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: foot Present Regionally restricted 5A Expression is in cartilage primordia in the joints.

Specimen 5: D,F: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: knee Present Regionally restricted 5D Expression is between the cartilage regions.

Specimen 6: A,C: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: renal capsule Present 6A
TS25: renal cortex Present Regionally restricted 6A Expression is in the connective tissue surrounding the glomeruli formation.
TS25: ovary Moderate 6A

Specimen 6: D,F: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: pericardium Moderate 6D
TS22: heart valve Present 6D

Specimen 6: G,I: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: testis cortical region Present Regionally restricted 6G Expression is in the tunica albuginea.
TS25: mediastinum testis Strong 6G
TS25: rete testis Strong 6G

Specimen 6: J,L: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: gut Present Regionally restricted 6J Expression is in the connective tissue capsule of the gut wall (the serosa), muscularis externa layer, and the lamina propria.

Specimen 7: A,C: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: cornea epithelium Present 7A
TS24: cornea stroma Present 7A

Specimen 7: D,F: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: vibrissa dermal component Present Regionally restricted 7D Expression is in the mesenchyme, moderate expression in the epithelium surrounding the hair follicle.

Specimen 7: G,I: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: cochlear duct mesenchyme Present Regionally restricted 7G Expression is in the surrounding mesenchyme of the cochlea.

Specimen 7: J,L: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: lung mesenchyme Present Regionally restricted 7J Expression is in the mesenchyme surrounding the epithelial layer of the developing cartilagenous bronchi of the lungs.
TS23: trachea cartilaginous ring Moderate Regionally restricted 7J Expression is in the cartilage surrounding the trachea.
TS23: trunk mesenchyme Moderate Regionally restricted 7J Expression in the mesenchymal tissue surrounding the aorta.
TS23: esophagus mesenchyme Moderate Regionally restricted 7J Expression is in the mesenchyme and smooth muscle layers.

Specimen 8: A,C: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: optic stalk Present Regionally restricted 8A Expression is in the dura mater of the optic nerve stalk.
TS25: sclera Present 8A

Specimen 8: D,F: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: trigeminal ganglion Present Graded 8D There is an apparent increased signal in the caudal half.

Specimen 8: G,I: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: remnant of Rathke's pouch Present Regionally restricted 8G Expression is in the epithelial wall.

Specimen 9: A,C: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: skeletal muscle Present Regionally restricted 9A Expression is in the epimysium surrounding the muscle fiber bundles.

Specimen 9: D,F: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: diaphragm Present 9D

Specimen 9: G,I: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: heart valve Present 9G

Specimen 9: J,L: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: axial skeleton tail region Present 9J Expression is the areas where muscle contacts the vertebral bone.

Specimen Table 1, E12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cartilage Present Regionally restricted Expression is in pre-chondrocytic mesenchymal cells, the primordial cartilage condensations.
TS20: skeleton Present Regionally restricted Expression is in pre-chondrocytic mesenchymal cells, the primordial cartilage condensations.
TS20: left lung lobar bronchus Present
TS20: right lung lobar bronchus Present
TS20: gonad Present Regionally restricted Expression is in the capsule.
TS20: intestine Present Regionally restricted Expression is in the capsule.
TS20: metanephros Present Regionally restricted Expression is in the capsule.
TS20: pericardium Present

Specimen Table 1, E13.5: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cartilage Present Regionally restricted Expression is in the primordial cartilage condensations, the pre-chondrocytic mesenchymal cells in axial, craniofacial, and appendicular primordial cartilage.
TS21: skeleton Present Regionally restricted Expression is in the primordial cartilage condensations, the pre-chondrocytic mesenchymal cells in axial, craniofacial, and appendicular primordial cartilage.
TS21: lobar bronchus Present
TS21: intestine Present Regionally restricted Expression is in the capsule.
TS21: ovary Present Regionally restricted Expression is in the capsule.
TS21: testis Present Regionally restricted Expression is in the capsule.
TS21: metanephros Present Regionally restricted Expression is in the capsule.
TS21: pericardium Present
TS21: cochlea Present

Specimen Table 1, E14.5: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: skeleton Present Regionally restricted Expression is in the primordial cartilage condensations.
TS22: lobar bronchus Present
TS22: intestine Present Regionally restricted Expression is in the capsule.
TS22: metanephros Present Regionally restricted Expression is in the capsule.
TS22: ovary Present Regionally restricted Expression is in the capsule.
TS22: testis Present Regionally restricted Expression is in the capsule.
TS22: pericardium Present
TS22: cochlea Present
TS22: remnant of Rathke's pouch Present
TS22: trigeminal ganglion Present
TS22: vibrissa Present

Specimen Table 1, E15.5: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: trachea cartilaginous ring Present
TS23: diaphragm Present
TS23: skeletal muscle Present Regionally restricted Expression is in the epimysium and the myotendinous junctions.
TS23: heart valve Present
TS23: cornea epithelium Present
TS23: cornea stroma Present
TS23: cochlea Present
TS23: vibrissa Present
TS23: lobar bronchus Present
TS23: intestine Present Regionally restricted Expression is in the capsule.
TS23: ovary Present Regionally restricted Expression is in the capsule.
TS23: testis Present Regionally restricted Expression is in the capsule.
TS23: metanephros Present Regionally restricted Expression is in the capsule.
TS23: eye Present Regionally restricted Expression is in the sclera.
TS23: spinal cord dura mater Present
TS23: aorta Present
TS23: esophagus Present
TS23: pericardium Present

Specimen Table 1, E16.5: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: axial skeleton Present Regionally restricted Expression is in pre-hypertrophic chondrocytes, articular cartilage and joints, and in intrachondral/intramembranous ossification.
TS24: axial musculature Present Regionally restricted Expression is in the epimysium, myotendinous junctions, tendons and ligaments.
TS24: diaphragm Present
TS24: heart valve Present
TS24: cochlea Present
TS24: cornea epithelium Present
TS24: cornea stroma Present
TS24: vibrissa Present
TS24: lobar bronchus Present
TS24: renal capsule Present
TS24: tunica albuginea of ovary Present
TS24: intestine Present Regionally restricted Expression is in the capsule.
TS24: testis Present Regionally restricted Expression is in the capsule.
TS24: spinal cord dura mater Present
TS24: sclera Present

Specimen Table 1, E17.5: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: axial skeleton Present Regionally restricted Expression is in pre-hypertrophic chondrocytes, articular cartilage and joints, and in intrachondral/intramembranous ossification.
TS25: skeletal muscle Present Regionally restricted Expression is in the epimysium, myotendinous junctions, tendons and ligaments.
TS25: diaphragm Present
TS25: heart valve Present
TS25: cochlea Present
TS25: cornea epithelium Present
TS25: cornea stroma Present
TS25: vibrissa Present
TS25: lobar bronchus Present
TS25: renal capsule Present
TS25: tunica albuginea of ovary Present
TS25: intestine Present Regionally restricted Expression is in the capsule.
TS25: testis Present Regionally restricted Expression is in the capsule.
TS25: sclera Present
TS25: spinal cord dura mater Present

Specimen Table 1, E18.5: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: skeleton Present Regionally restricted Expression is in pre-hypertrophic chondrocytes, articular cartilage and joints, and in intrachondral/intramembranous ossification.
TS26: skeletal muscle Present Regionally restricted Expression is in the epimysium, myotendinous junctions, tendons and ligaments.
TS26: heart valve Present
TS26: cochlea Present
TS26: cornea epithelium Present
TS26: cornea stroma Present
TS26: vibrissa Present
TS26: lobar bronchus Present
TS26: renal capsule Present
TS26: tunica albuginea of ovary Present
TS26: intestine Present Regionally restricted Expression is in the capsule.
TS26: testis Present Regionally restricted Expression is in the capsule.
TS26: spinal cord dura mater Present
TS26: sclera Present


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory