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Gene Expression Data
Assay Details
Assay
Reference: J:69388 Grimmond S, et al., Expression of a novel mammalian epidermal growth factor-related gene during mouse neural development. Mech Dev. 2001 Apr;102(1-2):209-11
Assay type: RNA in situ
MGI Accession ID: MGI:2677015
Gene symbol: Scube2
Gene name: signal peptide, CUB domain, EGF-like 2
Probe: Cegf1 cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 2A: embryonic day 8.0 (more )
Note: 4 Somite embryo.
Structure Level Pattern Image Note
TS12: future prosencephalon Present 2A
TS12: future spinal cord Present 2A
TS12: anterior pro-rhombomere Weak 2A
TS12: future midbrain Absent 2A

Specimen 2B: embryonic day 8.5 (more )
Note: 8 Somite embryo.
Structure Level Pattern Image Note
TS13: future prosencephalon Present 2B
TS13: future spinal cord Present 2B
TS13: future hindbrain Present Regionally restricted 2B Expression spreads dorsally through the hindbrain.
TS13: future midbrain Absent 2B
TS13: rhombomere 1 Absent 2B

Specimen 2C: embryonic day 8.5 (more )
Note: 12 Somite embryo. A lateral view of the embryo shown in section in (G) and (H).
Structure Level Pattern Image Note
TS13: future prosencephalon Present 2C
TS13: future hindbrain Present Regionally restricted 2C
TS13: future midbrain Absent 2C
TS13: rhombomere 1 Absent 2C

Specimen 2D: embryonic day 9.5 (more )
Note: 23 Somite embryo.
Structure Level Pattern Image Note
TS15: diencephalon Present Regionally restricted 2D Expression is dorsal.
TS15: telencephalon Present Regionally restricted 2D Expression is dorsal in the posterior telencephalon.
TS15: optic cup Present 2D
TS15: rhombomere 2 Present 2E , 2D
TS15: rhombomere 3 Present 2E , 2D
TS15: rhombomere 4 Present 2E , 2D
TS15: rhombomere 5 Present 2E , 2D
TS15: rhombomere 6 Present 2E , 2D
TS15: rhombomere 7 Present 2E , 2D
TS15: rhombomere 8 Present 2E , 2D
TS15: future midbrain Absent 2D , 2E
TS15: otocyst Absent 2D , 2E
TS15: rhombomere 1 Absent 2D , 2E

Specimen 2F: embryonic day 10.0 (more )
Note: 34 Somite embryo.
Structure Level Pattern Image Note
TS16: diencephalon Present Regionally restricted 2F Expression is dorsal.
TS16: telencephalon Present Regionally restricted 2F Expression is dorsal in the posterior telencephalon.
TS16: optic cup Present 2F
TS16: rhombomere 2 Present 2F
TS16: rhombomere 3 Present 2F
TS16: rhombomere 4 Present 2F
TS16: rhombomere 5 Present 2F
TS16: rhombomere 6 Present 2F
TS16: rhombomere 7 Present 2F
TS16: rhombomere 8 Present 2F
TS16: future midbrain Absent 2F
TS16: otocyst Absent 2F
TS16: rhombomere 1 Absent 2F

Specimen 2G: embryonic day 8.5 (more )
Note: 12 Somite embryo.
Structure Level Pattern Image Note
TS13: future prosencephalon Present Regionally restricted 2G Expression is in the lateral neural folds.
TS13: future hindbrain Present Regionally restricted 2G Expression remains in a more ventral region of the hindbrain.

Specimen 2H: embryonic day 8.5 (more )
Note: 12 Somite embryo.
Structure Level Pattern Image Note
TS13: neural tube Present Regionally restricted 2H Expression is in the dorsal half of the neural tube but is absent in the dorsal midline neurectoderm.
TS13: neural tube roof plate Absent 2H

Specimen 2I: embryonic day 9.5 (more )
Note: 23 Somite embryo. Section through the forebrain (left) and midbrain (right) of the embryo shown in (D).
Structure Level Pattern Image Note
TS15: future forebrain Present Regionally restricted 2I Expression is dorsal.
TS15: future hindbrain Present Regionally restricted 2I Expression remains in a more ventral region of the hindbrain.
TS15: future midbrain Absent 2I

Specimen 2J: embryonic day 12.5 (more )
Note: Vibratome section.
Structure Level Pattern Image Note
TS20: spinal cord Present Regionally restricted 2J Expression is dorsal.

Specimen Not Shown: embryonic day 12.5 (more )
Note: Vibratome section.
Structure Level Pattern Image Note
TS20: diencephalon Present Regionally restricted Expression is dorsal.

Specimen Not Shown: embryonic day 14.5 (more )
Note: Vibratome section.
Structure Level Pattern Image Note
TS22: embryo Absent


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory