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Gene Expression Data
Assay Details
Assay
Reference: J:82167 White PH, et al., Defective somite patterning in mouse embryos with reduced levels of Tbx6. Development. 2003 Apr;130(8):1681-90
Assay type: RNA in situ
MGI Accession ID: MGI:2676980
Gene symbol: Tbx6
Gene name: T-box 6
Probe: Tbx6 probe2
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1E: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: tail unsegmented mesenchyme Present 1E Expression in presomitic mesoderm prior to somite segmentation.
TS15: trunk somite Absent 1E
Specimen 4F, rv/rv (left): embryonic day 10.5; Tbx6rv/Tbx6rv (more )
Note: Dorsal view.
Structure Level Pattern Image Note
TS17: tail unsegmented mesenchyme Present Regionally restricted 4F rv/rv (left) Authors report correct spatial pattern but lower transcript levels compared with rv/+ tails.
Specimen 4F, rv/rv (right): embryonic day 10.5; Tbx6rv/Tbx6rv (more )
Note: Side view.
Structure Level Pattern Image Note
TS17: tail unsegmented mesenchyme Present Regionally restricted 4F rv/rv (right) Authors report correct spatial pattern but lower transcript levels compared with rv/+ tails.
Specimen 4F, rv/+ (left): embryonic day 10.5; Tbx6rv/Tbx6+ (more )
Note: Dorsal view.
Structure Level Pattern Image Note
TS17: tail unsegmented mesenchyme Present Regionally restricted 4F rv/+ (left)
Specimen 4F, rv/+ (right): embryonic day 10.5; Tbx6rv/Tbx6+ (more )
Note: Side view.
Structure Level Pattern Image Note
TS17: tail unsegmented mesenchyme Present Regionally restricted 4F rv/+ (right)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
MGI 6.23 		The Jackson Laboratory