Summary | Transgene origin | Transgene description | Phenotypes | Find Mice (IMSR) | Notes | References

Symbol:	Tg(SMN2)566Ahmb
Name:	transgene insertion 566, Arthur H M Burghes
MGI ID:	MGI:2676920
Transgene:	Tg(SMN2)566Ahmb  Location: unknown
Alliance:	Tg(SMN2)566Ahmb page

Strain of Origin:

FVB

Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence) Mutation:    Insertion   Tg(SMN2)566Ahmb expresses 1 gene Transgene expresses: Organism Expressed Gene Homolog in Mouse Note human SMN2 (6607) Smn1  (MGI:109257)   Mutation details: A 35.5 kb genomic fragment containing human SMN2 used for the transgene. The transgene is ubiquitously expressed in all tissues examined by Northern blot analysis. Line 566 carries 8 copies of the transgene. (J:60592)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:60592 Monani UR, et al., The human centromeric survival motor neuron gene (SMN2) rescues embryonic lethality in Smn(-/-) mice and results in a mouse with spinal muscular atrophy. Hum Mol Genet. 2000 Feb 12;9(3):333-9
All:	3 reference(s)