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Gene Expression Data
Assay Details
Assay
Reference: J:60424 Egeo A, et al., Developmental expression of the SH3BGR gene, mapping to the Down syndrome heart critical region. Mech Dev. 2000 Feb;90(2):313-6
Assay type: RNA in situ
MGI Accession ID: MGI:2675123
Gene symbol: Sh3bgr
Gene name: SH3-binding domain glutamic acid-rich protein
Probe: Sh3bgr cDNA
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 3A/B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cardiac muscle tissue Present 3A/B
TS20: urinary system Present Regionally restricted 3A/B Expression is in the muscular wall of the bladder.
TS20: right atrium valve Absent 3A/B
TS20: tail somite Absent 3A/B
Specimen Not Shown: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: skeletal muscle Present Regionally restricted Expression is first detected in the head muscles.
Specimen 3C: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cardiac muscle tissue Present 3C
TS21: vertebral axis musculature Present 3C Expression is in muscles in the trunk.
TS21: esophagus Present 3C
Specimen 3D/E: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cardiac muscle tissue Present 3D/E
TS21: interventricular septum Present Regionally restricted 3D/E Expression in the myocardium, but is absent in the membranous portion.
TS21: heart valve Absent 3D/E
TS21: right atrium valve Absent 3D/E
Specimen 3F/G: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: pulmonary vein Strong 3F/G
TS23: esophagus Present Regionally restricted 3F/G Expression is in smooth muscle.
TS23: intestine Present Regionally restricted 3F/G Expression is in smooth muscle.
Specimen 3I: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: limb musculature Present 3I
Specimen 3L: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: cardiac muscle tissue Present 3L
Specimen Not Shown: postnatal adult (more )
Structure Level Pattern Image Note
TS28: cardiac muscle tissue Present
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory