Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | Notes | References

Symbol:	RttnGt(pGT1.8geo)7Pgr
Name:	rotatin; gene trap 7, Peter Gruss
MGI ID:	MGI:2674124
Synonyms:	rotatinGT, XV-53
Gene:	Rttn  Location: Chr18:88989914-89149140 bp, + strand  Genetic Position: Chr18, 58.93 cM
Alliance:	RttnGt(pGT1.8geo)7Pgr page

Mutant Cell Line:	XV-53
Germline Transmission:	Earliest citation of germline transmission: J:76233
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Gene trapped (Null/knockout, Reporter) Mutation:    Insertion of gene trap vector     Vector: IRESbetageo     Vector Type: gene trap   Mutation details: An integration of the gene trap vector occurred such that the splice donor at position 1101 to 1102 of the cDNA becomes fused to the splice acceptor in the vector DNA. A protein consisting of the first 281 amino acids of the Rttn gene fused to the beta-galactosidase/neomycin gene is expressed from this allele. (J:76233)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	72 assay results
In Structures Affected by this Mutation:	4 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Rttn Mutation:	99 strains or lines available

Original:	J:47980 Stoykova A, et al., Gene trap expression and mutational analysis for genes involved in the development of the mammalian nervous system. Dev Dyn. 1998 Jun;212(2):198-213
All:	2 reference(s)