Gene Expression Data
Assay Details
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Assay
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Reference:
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J:82458
Davenport TG, et al., Mammary gland, limb and yolk sac defects in mice lacking Tbx3, the gene mutated in human ulnar mammary syndrome. Development. 2003 May;130(10):2263-73
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:2674061
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Gene symbol:
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Tbx2
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Gene name:
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T-box 2
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Probe:
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Tbx2 probe3
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Assay notes:
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Some experiments may also have been performed on Swiss-Webster and ICR backgrounds. Authors state that identical phenotypes were seen on all backgrounds, and therefore all data was combined.
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Results
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Specimen
5B +/-:
embryonic day 11.5; Tbx3tm1Pa/Tbx3 +
(more  )
Specimen
5B +/-:
(close  )
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Genetic Background:
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either: (involves: 129 * 129S1/Sv * 129X1/SvJ) or (involves: 129 * 129S1/Sv * 129X1/SvJ * C57BL/6NTac)
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Mutant Allele(s):
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Tbx3tm1Pa/Tbx3+
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: forelimb bud |
Present |
Regionally restricted |
5B +/-
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Expression was detected at the anterior and posterior margins of the limb buds.
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| TS19: hindlimb bud |
Present |
Regionally restricted |
5B +/-
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Expression was detected at the anterior and posterior margins of the limb buds.
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Specimen
5B -/-:
(close )
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Genetic Background:
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either: (involves: 129 * 129S1/Sv * 129X1/SvJ) or (involves: 129 * 129S1/Sv * 129X1/SvJ * C57BL/6NTac)
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Mutant Allele(s):
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Tbx3tm1Pa/Tbx3tm1Pa
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Age:
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embryonic day 11.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS19: forelimb bud |
Present |
Regionally restricted |
5B -/-
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Expression was present in the anterior margin (as in wild type) but weak in the posterior margin of the forelimb bud.
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| TS19: hindlimb bud |
Present |
Regionally restricted |
5B -/-
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Expression was present in the anterior margin (as in wild type) but absent in the posterior margin of the hindlimb bud.
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Analysis Tools
