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Gene Expression Data
Assay Details
Assay
Reference: J:34235 Luo ZD, et al., Acetylcholinesterase and nicotinic acetylcholine receptor expression diverge in muscular dysgenic mice lacking the L-type calcium channel. J Neurochem. 1996 Jul;67(1):111-8
Assay type: RNase protection
MGI Accession ID: MGI:2672124
Gene symbol: Chrna1
Gene name: cholinergic receptor nicotinic alpha 1 subunit
Probe: alpha-nAChR cDNA1
Probe preparation: Antisense labelled with P32 RNA
Visualized with: Autoradiography
Results Image: 1_[a]-nAChR SKM
 Sample Information Bands Other Sample Information
Lane AgeStructure 200 bp (a) Amount Genetic BackgroundMutant Allele(s)Sex
NB +/+ P newborn TS27: skeletal muscle Present Not Specified; total RNA Not Specified Pooled
NB mdg/mdg P newborn TS27: skeletal muscle Present Not Specified; total RNA involves: 129P1/ReJ * STOCK T/t4 Cacna1smdg/Cacna1smdgNot Specified
NB mdg/mdg P newborn TS27: skeletal muscle Present Not Specified; total RNA involves: 129P1/ReJ * STOCK T/t4 Cacna1smdg/Cacna1smdgNot Specified
E18 +/+ E18.0 (b) TS26: skeletal muscle Present Not Specified; total RNA Not Specified Pooled
E18 mdg/mdg E18.0 (b) TS26: skeletal muscle Present Not Specified; total RNA involves: 129P1/ReJ * STOCK T/t4 Cacna1smdg/Cacna1smdgPooled
mdg/mdg E18.0 (b) TS26: skeletal muscle Present Not Specified; total RNA involves: 129P1/ReJ * STOCK T/t4 Cacna1smdg/Cacna1smdgPooled
Notes:
(a) Expression levels are lower in E18 mice than in newborns. In mutants, the expression levels increased compared to controls.
(b) Age of embryo at noon of plug day not specified in reference.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/30/2024
MGI 6.23 		The Jackson Laboratory