Summary | Transgene origin | Transgene description | Recombinase activity | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(Col2a1-cre)1Star
Name:	transgene insertion 1, Rene St-Arnaud
MGI ID:	MGI:2671895
Synonyms:	alpha1(II)-Cre, alphaI(II)-collagen-cre, Col2-Cre
Transgene:	Tg(Col2a1-cre)1Star  Location: unknown
Alliance:	Tg(Col2a1-cre)1Star page

Strain of Origin:

C57BL/6

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(Col2a1-cre)1Star expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Col2a1 (MGI:88452)   Mutation details: Bacterial Cre recombinase cDNA was subcloned between a 3 kb fragment of the mouse Col2a1 promoter and its chondrocyte-specific enhancer region. Transgenic founders were generated by pronuclear injection. Confirmation that Cre was expressed as expected was accomplished by crossing transgenic mice with mice carrying the Rosa26 reporter gene (J:84273)

Activity:	Tissue activity of this recombinase allele
Driver:	Col2a1 (mouse) Summary of all recombinase alleles driven by Col2a1. Comparative matrix view of recombinase activities Alliance mouse Col2a1 gene page

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:84273 Terpstra L, et al., Reduced chondrocyte proliferation and chondrodysplasia in mice lacking the integrin-linked kinase in chondrocytes. J Cell Biol. 2003 Jul 7;162(1):139-48
All:	25 reference(s)