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Gene Expression Data
Assay Details
Assay
Reference: J:60967 Uren D, et al., Gene dosage affects the cardiac and brain phenotype in nonmuscle myosin II-B-depleted mice. J Clin Invest. 2000 Mar;105(5):663-71
Assay type: Western blot
MGI Accession ID: MGI:2669220
Gene symbol: Myh10
Gene name: myosin, heavy polypeptide 10, non-muscle
Antibody: Anti-NMHC-B
Results
Image: 2a ©

 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Genetic BackgroundMutant Allele(s)Sex
Lung +/+ E14.5 (a) TS22: lung Present involves: 129S4/SvJae * C57BL/6J Not Specified
Lung +/deltaI E14.5 (a) TS22: lung Present involves: 129S4/SvJae * C57BL/6J Myh10tm1Rsad/Myh10+Not Specified
Lung deltaI/deltaI E14.5 (a) TS22: lung Present (b) involves: 129S4/SvJae * C57BL/6J Myh10tm1Rsad/Myh10tm1RsadNot Specified
Brain +/+ E14.5 (a) TS22: brain Present involves: 129S4/SvJae * C57BL/6J Not Specified
Brain +/deltaI E14.5 (a) TS22: brain Present involves: 129S4/SvJae * C57BL/6J Myh10tm1Rsad/Myh10+Not Specified
Brain deltaI/deltaI E14.5 (a) TS22: brain Present (c) involves: 129S4/SvJae * C57BL/6J Myh10tm1Rsad/Myh10tm1RsadNot Specified
Heart deltaI/deltaI E14.5 (a) TS22: heart Present (d) involves: 129S4/SvJae * C57BL/6J Myh10tm1Rsad/Myh10tm1RsadNot Specified
Heart +/deltaI E14.5 (a) TS22: heart Present involves: 129S4/SvJae * C57BL/6J Myh10tm1Rsad/Myh10+Not Specified
Heart +/+ E14.5 (a) TS22: heart Present involves: 129S4/SvJae * C57BL/6J Not Specified
Notes:
(a) Age of embryo at noon of plug day not specified in reference.
(b) Expression levels were decreased by 64% in mutant compared to wild type.
(c) Expression levels were decreased by 65% in mutant compared to wild type.
(d) Expression levels were decreased by 88% in mutant compared to wild type.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory