Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	S100a4tm1Egn
Name:	S100 calcium binding protein A4; targeted mutation 1, Eric G Neilson
MGI ID:	MGI:2665826
Synonyms:	FSP1GFP/GFP, FSP1 KO
Gene:	S100a4  Location: Chr3:90511077-90513349 bp, + strand  Genetic Position: Chr3, 39.27 cM, cytoband F1-F2
Alliance:	S100a4tm1Egn page

Germline Transmission:	Earliest citation of germline transmission: J:83971
Parent Cell Line:	TL1/TL-1 (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion   Mutation details: Parts of exon 2 and exon 3 were replaced in frame with GFP. Absence of gene product in fibroblasts from homozygous mice was demonstrated immunologically. (J:83971)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any S100a4 Mutation:	24 strains or lines available

Original:	J:83971 Xue C, et al., The gatekeeper effect of epithelial-mesenchymal transition regulates the frequency of breast cancer metastasis. Cancer Res. 2003 Jun 15;63(12):3386-94
All:	20 reference(s)