Tg(Myh6-tTA)6Smbf Transgene Detail MGI Mouse (MGI:2665551)

Tg(Myh6-tTA)6Smbf
Transgene Detail

Summary

Symbol:	Tg(Myh6-tTA)6Smbf
Name:	transgene insertion 6, Section of Myocardial Biology - Fishman Lab
MGI ID:	MGI:2665551
Synonyms:	2.9alphatTA, alphaMHC-tTA, alphaMtTA, Tg(MHCAtTA)6Smbf
Transgene:	Tg(Myh6-tTA)6Smbf Location: unknown
Alliance:	Tg(Myh6-tTA)6Smbf page

Transgene
origin

Strain of Origin:

Transgene
description

Transgene Type:		Transgenic (Transactivator)
Mutation:		Insertion
		Mutation details: The transgene consists of a rat Myh6 promoter and a tetracycline transactivator sequence. Transgene expression in cardiac tissue was confirmed by Northern blot analysis. 2.9 kb of rat Myh6 promoter sequences directs transgene expression in the heart starting at embryonic day E7.5. (J:82692)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Disease models

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 4 strains available Cell Lines: 0 lines available

Notes

Transgenic line 6 showed the strongest cardiac transgene expression and was used for analysis.

References

Original:	J:82692 Yu Z, et al., Conditional transgene expression in the heart. Circ Res. 1996 Oct;79(4):691-7
All:	83 reference(s)

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