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Tg(H2-Ea-H2-Ab1)1Pmr
Transgene Detail
Summary
Symbol: Tg(H2-Ea-H2-Ab1)1Pmr
Name: transgene insertion 1, Phillipa Marrack
MGI ID: MGI:2665485
Synonyms: AbEp
Transgene: Tg(H2-Ea-H2-Ab1)1Pmr  Location: unknown  
Alliance: Tg(H2-Ea-H2-Ab1)1Pmr page
Transgene
origin
Strain of Origin:  (C57BL/6 x SJL)F2
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(H2-Ea-H2-Ab1)1Pmr expresses 2 genes
 
Mutation detailsThe transgene consists of an H2-Ea promoter and an H2-Ab1 beta chain sequence covalently bound to the Ealpha peptide (52-68) by a gly,ser flexible linker. (J:58036)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Notes
Construction of the transgene is described in Ignatowicz (1995) J. Immunol. 154, 3852-3862.
References
Original:  J:58036 Ignatowicz L, et al., The repertoire of T cells shaped by a single MHC/peptide ligand. Cell. 1996 Feb 23;84(4):521-9
All:  16 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory