Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Pde6brd1-2J
Name:	phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide; retinal degeneration 1, 2 Jackson
MGI ID:	MGI:2665102
Synonyms:	neuroscience mutagenesis facility, 137, nmf137, NMF137, Pde6b2J, Pde6bnmf137
Gene:	Pde6b  Location: Chr5:108536239-108579609 bp, + strand  Genetic Position: Chr5, 53.07 cM
Alliance:	Pde6brd1-2J page

Strain of Origin:

C57BL/6J

Allele Type:    Chemically induced (ENU) Mutation:    Nucleotide substitutions   Mutation details: This mutation was shown by genetic complementation analysis to be an allele of Pde6b. Molecular sequence analysis showed that this mutation corresponds to a point mutation in exon 16. (J:122722) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pde6b Mutation:	119 strains or lines available

Original:	J:122722 Chang B, et al., Two mouse retinal degenerations caused by missense mutations in the beta-subunit of rod cGMP phosphodiesterase gene. Vision Res. 2007 Mar;47(5):624-33
All:	13 reference(s)