Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Serpinf1tm1Craw
Name:	serine (or cysteine) peptidase inhibitor, clade F, member 1; targeted mutation 1, Susan E Crawford
MGI ID:	MGI:2664515
Synonyms:	PEDF null
Gene:	Serpinf1  Location: Chr11:75300855-75313449 bp, - strand  Genetic Position: Chr11, 45.87 cM
Alliance:	Serpinf1tm1Craw page

Germline Transmission:	Earliest citation of germline transmission: J:83748
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion   Mutation details: A genomic fragment encompassing exons 3 through 6 was replaced with a cassette containing IRES-lacZ followed by floxed neo. (J:83748)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	10 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Serpinf1 Mutation:	26 strains or lines available

Original:	J:83748 Doll JA, et al., Pigment epithelium-derived factor regulates the vasculature and mass of the prostate and pancreas. Nat Med. 2003 Jun;9(6):774-80
All:	11 reference(s)