Carm1tm1Mtb
Targeted Allele Detail
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Symbol: |
Carm1tm1Mtb |
Name: |
coactivator-associated arginine methyltransferase 1; targeted mutation 1, Mark T Bedford |
MGI ID: |
MGI:2663959 |
Synonyms: |
Carm1- |
Gene: |
Carm1 Location: Chr9:21458163-21500763 bp, + strand Genetic Position: Chr9, Syntenic
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Alliance: |
Carm1tm1Mtb page
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Germline Transmission: |
Earliest citation of germline transmission:
J:83623
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Parent Cell Line: |
TC1/TC-1 (ES Cell)
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Strain of Origin: |
129S6/SvEvTac
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Allele Type: |
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Targeted (Conditional ready, Null/knockout) |
Mutation: |
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Insertion
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Mutation details: An FRT site flanked neomycin resisatnce gene cassette was inserted upstream of two exons encoding a portion of the cofactor binding domain (amino acids 117-187). Additionally, the inserted neo cassette and the two exons were flanked by a single loxP sites. Protein was undetected in homozygous mutant mice.
(J:83623)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Carm1 Mutation: |
93 strains or lines available
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Original: |
J:83623 Yadav N, et al., Specific protein methylation defects and gene expression perturbations in coactivator-associated arginine methyltransferase 1-deficient mice. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6464-8 |
All: |
11 reference(s) |
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