Agrntm4Jrs
Targeted Allele Detail
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Symbol: |
Agrntm4Jrs |
Name: |
agrin; targeted mutation 4, Joshua R Sanes |
MGI ID: |
MGI:2663725 |
Synonyms: |
AGD-, agrin-, AgrnDel, Agrntm1Klee |
Gene: |
Agrn Location: Chr4:156249747-156281945 bp, - strand Genetic Position: Chr4, 88.55 cM
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Alliance: |
Agrntm4Jrs page
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Germline Transmission: |
Earliest citation of germline transmission:
J:83827
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Null/knockout) |
Mutation: |
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Intragenic deletion
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Mutation details: The endogenous locus was disrupted by the removal of a genomic fragment extending from within exon 6 into intron 33 (~9 kb). The deletion removed sequence encoding both the neural and non-neural isoforms. Protein was undetected in homozygous mutant mice by immunohistochemical and Western blot analyses.
(J:83827)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Agrn Mutation: |
101 strains or lines available
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Original: |
J:83827 Lin W, et al., Distinct roles of nerve and muscle in postsynaptic differentiation of the neuromuscular synapse. Nature. 2001 Apr 26;410(6832):1057-64 |
All: |
17 reference(s) |
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