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Gene Expression Data
Assay Details
Assay
Reference: J:27616 Semsei I, et al., Tissue and age specific expression of the myc proto-oncogene family throughout the life span of the C57BL/6J mouse strain. Oncogene. 1989 Apr;4(4):465-71
Assay type: Northern blot
MGI Accession ID: MGI:2659048
Gene symbol: Myc
Gene name: myelocytomatosis oncogene
Probe: pSVc-myc1
Probe preparation: Double stranded labelled with P32 DNA
Visualized with: Autoradiography
Assay notes: Expression levels are quantified in other figures in the paper. In general, expression was highest in newborn animals, decreasing to its lowest levels at about 3-10 months of age. With the increase in age, there was an increase in expression in some organs (brain, liver, skin, and small intestine), and little or no change in other organs (kidney, spleen, and heart). The highest absolute level of expression was found in the spleen; it is about 10 fold higher than brain, which had the lowest level of expression at adult stages.
Results Image: 2_c-myc
 Sample Information Bands Other Sample Information
Lane AgeStructure 2.4 kb Amount Genetic BackgroundMutant Allele(s)Sex Note
Brain 1 P newborn TS27: brain Present 25 µg; total RNA C57BL/6J Male
Brain 2 P m 2 TS28: brain Present 25 µg; total RNA C57BL/6J Male
Brain 3 P m 6 TS28: brain Present 25 µg; total RNA C57BL/6J Male
Brain 4 P m 12 TS28: brain Present 25 µg; total RNA C57BL/6J Male
Brain 5 P m 24 TS28: brain Present 25 µg; total RNA C57BL/6J Male
Brain 6 P m 32 TS28: brain Present 25 µg; total RNA C57BL/6J Male
Heart 1 P newborn TS27: heart Present 25 µg; total RNA C57BL/6J Male
Heart 2 P m 2 TS28: heart Present 25 µg; total RNA C57BL/6J Male
Heart 3 P m 6 TS28: heart Present 25 µg; total RNA C57BL/6J Male
Heart 4 P m 12 TS28: heart Present 25 µg; total RNA C57BL/6J Male
Heart 5 P m 24 TS28: heart Present 25 µg; total RNA C57BL/6J Male
Heart 6 P m 32 TS28: heart Present 25 µg; total RNA C57BL/6J Male
Intestine 1 P newborn TS27: small intestine Present 25 µg; total RNA C57BL/6J Male
Intestine 2 P m 2 TS28: small intestine Present 25 µg; total RNA C57BL/6J Male
Intestine 3 P m 6 TS28: small intestine Present 25 µg; total RNA C57BL/6J Male
Intestine 4 P m 12 TS28: small intestine Present 25 µg; total RNA C57BL/6J Male
Intestine 5 P m 24 TS28: small intestine Present 25 µg; total RNA C57BL/6J Male
Intestine 6 P m 32 TS28: small intestine Present 25 µg; total RNA C57BL/6J Male
Kidney 1 P newborn TS27: metanephros Present 25 µg; total RNA C57BL/6J Male
Kidney 2 P m 2 TS28: metanephros Present 25 µg; total RNA C57BL/6J Male
Kidney 3 P m 6 TS28: metanephros Present 25 µg; total RNA C57BL/6J Male
Kidney 4 P m 12 TS28: metanephros Present 25 µg; total RNA C57BL/6J Male
Kidney 5 P m 24 TS28: metanephros Present 25 µg; total RNA C57BL/6J Male
Kidney 6 P m 32 TS28: metanephros Present 25 µg; total RNA C57BL/6J Male
Liver 1 P newborn TS27: liver Present 25 µg; total RNA C57BL/6J Male
Liver 2 P m 2 TS28: liver Present 25 µg; total RNA C57BL/6J Male
Liver 3 P m 6 TS28: liver Present 25 µg; total RNA C57BL/6J Male
Liver 4 P m 12 TS28: liver Present 25 µg; total RNA C57BL/6J Male
Liver 5 P m 24 TS28: liver Present 25 µg; total RNA C57BL/6J Male
Liver 6 P m 36 TS28: liver Present 25 µg; total RNA C57BL/6J Male
Skin 1 P newborn TS27: skin Present 25 µg; total RNA C57BL/6J Male shaved skin from the back area
Skin 2 P y 2 TS28: skin Present 25 µg; total RNA C57BL/6J Male shaved skin from the back area
Skin 3 P m 6 TS28: skin Present 25 µg; total RNA C57BL/6J Male shaved skin from the back area
Skin 4 P m 12 TS28: skin Present 25 µg; total RNA C57BL/6J Male shaved skin from the back area
Skin 5 P m 24 TS28: skin Present 25 µg; total RNA C57BL/6J Male shaved skin from the back area
Skin 6 P m 36 TS28: skin Present 25 µg; total RNA C57BL/6J Male shaved skin from the back area
Spleen 1 P newborn TS27: spleen Present 25 µg; total RNA C57BL/6J Male
Spleen 2 P m 2 TS28: spleen Present 25 µg; total RNA C57BL/6J Male
Spleen 3 P m 6 TS28: spleen Present 25 µg; total RNA C57BL/6J Male
Spleen 4 P m 12 TS28: spleen Present 25 µg; total RNA C57BL/6J Male
Spleen 5 P m 24 TS28: spleen Present 25 µg; total RNA C57BL/6J Male
Spleen 6 P m 32 TS28: spleen Present 25 µg; total RNA C57BL/6J Male
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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