Summary | Transgene origin | Transgene description | Recombinase activity | Tumor data | Find Mice (IMSR) | References

Symbol:	Tg(GFAP-cre)1Gtm
Name:	transgene insertion 1, David H Gutmann
MGI ID:	MGI:2656247
Synonyms:	GFAPCre, GFAP-Cre
Transgene:	Tg(GFAP-cre)1Gtm  Location: unknown
Alliance:	Tg(GFAP-cre)1Gtm page

Strain of Origin:

C57BL/6 x CBA

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(GFAP-cre)1Gtm expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Homolog in Mouse Note human GFAP (2670) Gfap  (MGI:95697)   Mutation details: This transgene expresses Cre recombinase and beta-galactosidase under the control of the human glial fibrillary acidic (GFAP) promoter. This transgene is expressed in astrocytes by embryonic day 14.5. Two lines 1 and 8 were analyzed further for cre activity and expression. Both gave identical results. (J:77208)

Activity:	Tissue activity of this recombinase allele
Driver:	GFAP (human) Summary of all recombinase alleles driven by GFAP. Comparative matrix view of recombinase activities Alliance human GFAP gene page

List all tumor models in MMHCdb carrying Tg(GFAP-cre)1Gtm

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:77208 Bajenaru ML, et al., Astrocyte-specific inactivation of the neurofibromatosis 1 gene (NF1) is insufficient for astrocytoma formation. Mol Cell Biol. 2002 Jul;22(14):5100-13
All:	13 reference(s)