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Tg(IL10)1Grx
Transgene Detail
Summary
Symbol: Tg(IL10)1Grx
Name: transgene insertion 1, Herve Groux
MGI ID: MGI:2447571
Synonyms: hIL-10 TG, hu10Tg
Transgene: Tg(IL10)1Grx  Location: unknown  
Alliance: Tg(IL10)1Grx page
Transgene
origin
Strain of Origin:  BALB/cJ
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(IL10)1Grx expresses 1 gene
 
Mutation detailsHuman IL10 sequence was adjoined to the class II MHC Ea promoter sequence (-2172 to +12). The MHC class II Ea promoter drove transgenic expression in MHC class II positive cells. (J:80948)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:80948 Groux H, et al., A transgenic model to analyze the immunoregulatory role of IL-10 secreted by antigen-presenting cells. J Immunol. 1999 Feb 1;162(3):1723-9
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory