Tg(CAG-CD81)1Uem Transgene Detail MGI Mouse (MGI:2447840)

Tg(CAG-CD81)1Uem
Transgene Detail

Summary

Symbol:	Tg(CAG-CD81)1Uem
Name:	transgene insertion 1, Yasushi Uematsu
MGI ID:	MGI:2447840
Synonyms:	Tg(ACTB-CD81)1Uem, Tg(CAG-CD81)1Uem
Transgene:	Tg(CAG-CD81)1Uem Location: unknown
Alliance:	Tg(CAG-CD81)1Uem page

Transgene
origin

Strain of Origin:

FVB

Transgene
description

Transgene Type:

Transgenic (Inserted expressed sequence)

Mutation:

Insertion

Tg(CAG-CD81)1Uem expresses 1 gene

Mutation details: The transgene consists of the CAG regulatory unit (a CMV early immediate enhancer, and a modified chicken actin beta promoter) as well as human CD81 cDNA flanked by rabbit beta-globin exon 3 sequences. Transgene RNA expression in all organs was verified by Northern blot analysis. Transgene protein expression on the cell surface of thymocytes, peripheral blood lymphocytes, and splenocytes was observed by cytofluorometric analysis. (J:80797)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

Original:	J:80797 Masciopinto F, et al., Expression of human CD81 in transgenic mice does not confer susceptibility to hepatitis C virus infection. Virology. 2002 Dec 20;304(2):187-96
All:	1 reference(s)

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