Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Cdontm2Rsk
Name:	cell adhesion molecule-related/down-regulated by oncogenes; targeted mutation 2, Robert S Krauss
MGI ID:	MGI:2653132
Synonyms:	CdonlacZ-2
Gene:	Cdon  Location: Chr9:35332836-35418948 bp, + strand  Genetic Position: Chr9, 20.24 cM
Alliance:	Cdontm2Rsk page

Germline Transmission:	Earliest citation of germline transmission: J:82221
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129/Sv

Allele Type:    Targeted (Null/knockout, Reporter) Mutation:    Insertion   Mutation details: An IRES-lacZ-neo cassette was inserted at the 3' terminus of exon 3. Endogenous protein was undetected by Western blot analysis of homozygous mutant mice. Beta-galactosidase activity was detected by staining. (J:82221)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	21 assay results
In Structures Affected by this Mutation:	15 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cdon Mutation:	66 strains or lines available

Original:	J:82221 Cole F, et al., Microform Holoprosencephaly in Mice that Lack the Ig Superfamily Member Cdon. Curr Biol. 2003 Mar 4;13(5):411-5
All:	13 reference(s)