Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol: Anxa1tm1Rjf Name: annexin A1; targeted mutation 1, Roderick J Flower MGI ID: MGI:2449710 Synonyms: annexin 1-, Anx-1-, AnxA1(-), ANXA1 KO Gene: Anxa1  Location: Chr19:20350798-20368035 bp, - strand  Genetic Position: Chr19, 13.83 cM Alliance: Anxa1tm1Rjf page

Anxa1tm1Rjf/Anxa1tm1Rjf mice exhibit a delay in colonic mucosal wound closure Show the 1 phenotype image(s) involving this allele.

Germline Transmission:	Earliest citation of germline transmission: J:81498
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion   Mutation details: A portion of exon 2 and all of exons 3 and 4 were replaced with a cassette containing lacZ and PGK-neo. Endogenous protein was undetected in homozygous mutant mice. lacZ expression was detected in various tissues. (J:81498)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	10 assay results
In Structures Affected by this Mutation:	12 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Anxa1 Mutation:	22 strains or lines available

Original:	J:81498 Hannon R, et al., Aberrant inflammation and resistance to glucocorticoids in annexin 1-/- mouse. FASEB J. 2003 Feb;17(2):253-5
All:	68 reference(s)