Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Cenpetm2Dwc
Name:	centromere protein E; targeted mutation 2, Don W Cleveland
MGI ID:	MGI:2449008
Synonyms:	CENP-E conditional
Gene:	Cenpe  Location: Chr3:134918324-134979301 bp, + strand  Genetic Position: Chr3, 62.55 cM, cytoband H2
Alliance:	Cenpetm2Dwc page

Germline Transmission:	Earliest citation of germline transmission: J:81046
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion     A 120 bp exon of the gene was flanked with a loxP site and a floxed PGK-neo cassette. (J:81046)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cenpe Mutation:	109 strains or lines available

Original:	J:81046 Putkey FR, et al., Unstable kinetochore-microtubule capture and chromosomal instability following deletion of CENP-E. Dev Cell. 2002 Sep;3(3):351-65
All:	1 reference(s)