Summary | Transgene origin | Transgene description | Expression | Recombinase activity | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(Gata1-cre)1Sho
Name:	transgene insertion 1, Stuart Orkin
MGI ID:	MGI:2446599
Synonyms:	GATA1-Cre
Transgene:	Tg(Gata1-cre)1Sho  Location: unknown
Alliance:	Tg(Gata1-cre)1Sho page

Strain of Origin:

CD-1

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(Gata1-cre)1Sho expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note mouse Gata1 (MGI:95661)   Mutation details: Sequence encoding cre recombinase was adjoined to the murine Gata1 promoter region. The expanded expression pattern (relative to the endogenous Gata1 gene) has been attributed to leaky cre expression during an early stage of embryogenesis. While the Gata1 promoter was putatively a hematopoietic-specific promoter, efficient cre mediated excision has been observed in germ cells. (J:64291)

Activity:	Tissue activity of this recombinase allele
Driver:	Gata1 (mouse) Summary of all recombinase alleles driven by Gata1. Comparative matrix view of recombinase activities Alliance mouse Gata1 gene page

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

20 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available

Original:	J:64291 Mao X, et al., Improved reporter strain for monitoring Cre recombinase-mediated DNA excisions in mice. Proc Natl Acad Sci U S A. 1999 Apr 27;96(9):5037-42
All:	26 reference(s)