Tg(Mt1-GHRH)1Lstu
Transgene Detail
|
|
| Symbol: |
Tg(Mt1-GHRH)1Lstu |
| Name: |
transgene insertion 1, Lucia Stefaneanu |
| MGI ID: |
MGI:2447439 |
| Synonyms: |
MT-hGRF |
| Transgene: |
Tg(Mt1-GHRH)1Lstu Location: unknown
|
| Alliance: |
Tg(Mt1-GHRH)1Lstu page
|
|
|
|
| Transgene Type: |
|
Transgenic (Inserted expressed sequence) |
| Mutation: |
|
Insertion
|
| |
|
Tg(Mt1-GHRH)1Lstu expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
GHRH (2691) |
|
|
|
| |
|
Mutation details: The transgene consists of a 220 bp fragment of the human GHRH gene encoding the N-terminal 31 amino acid signal peptide and a 40 amino acid form of the protein fused to a mouse Mt1 promoter. Overexpression of the human GHRH transgene was observed by in situ hybridization analysis of pituitary tumors from transgenic animals over 10 months of age.
(J:80892)
|
|
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
|
| Original: |
J:80892 Stefaneanu L, et al., Adenohypophysial changes in mice transgenic for human growth hormone-releasing factor: a histological, immunocytochemical, and electron microscopic investigation. Endocrinology. 1989 Nov;125(5):2710-8 |
| All: |
4 reference(s) |
|
Analysis Tools
