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Prmt1Gt(U3BetaGeo)7.4.2Rul
Gene trapped Allele Detail
Summary
Symbol: Prmt1Gt(U3BetaGeo)7.4.2Rul
Name: protein arginine N-methyltransferase 1; gene trap 7.4.2 H Earl Ruley
MGI ID: MGI:2448365
Synonyms: 7.4.2, Prmt1 -
Gene: Prmt1  Location: Chr7:44626179-44635844 bp, - strand  Genetic Position: Chr7, 29.07 cM
Alliance: Prmt1Gt(U3BetaGeo)7.4.2Rul page
Mutation
origin
Mutant Cell Line:  7.4.2
Germline Transmission:  Earliest citation of germline transmission: J:61432
Parent Cell Line:  D3H (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Gene trapped (Null/knockout, Reporter)
Mutation:    Insertion of gene trap vector     Vector: U3betageo     Vector Type: gene trap
 
Mutation detailsThe gene trap vector inserted into an intron of the gene. A beta-galactosidase fusion protein is expressed from this allele under the control of the endogenous promoter. (J:61432, J:151684)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 26 assay results
In Structures Affected by this Mutation: 4 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Prmt1 Mutation:  35 strains or lines available
References
Original:  J:61432 Pawlak MR, et al., Arginine N-methyltransferase 1 is required for early postimplantation mouse development, but cells deficient in the enzyme are viable. Mol Cell Biol. 2000 Jul;20(13):4859-69
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory