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Tg(rtetR-tetO-cre)1Mhz
Transgene Detail
Summary
Symbol: Tg(rtetR-tetO-cre)1Mhz
Name: transgene insertion 1, Martin Holzenberger
MGI ID: MGI:2447693
Synonyms: DAI-Cre
Transgene: Tg(rtetR-tetO-cre)1Mhz  Location: unknown  
Alliance: Tg(rtetR-tetO-cre)1Mhz page
Transgene
origin
Strain of Origin:  (C57BL/6 x CBA)F1
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    doxycycline/tetracycline
Mutation:    Insertion
 
Tg(rtetR-tetO-cre)1Mhz expression driven by 1 gene
 
Mutation detailsUpon induction with doxycycline, this transgene expresses both the rtTA activator and Cre recombinase from a bidirectional doxycycline responsive promoter (tetO) in most tissues. (J:69328)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: tetO (bacteria)
Summary of all recombinase alleles driven by tetO.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:69328 Holzenberger M, et al., Ubiquitous postnatal LoxP recombination using a doxycycline auto-inducible Cre transgene (DAI-Cre). Genesis. 2000 Feb;26(2):157-9
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory