Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Dnmt3ltm1Enl
Name:	DNA methyltransferase 3-like; targeted mutation 1, En Li
MGI ID:	MGI:2447127
Synonyms:	Dnmt3L -
Gene:	Dnmt3l  Location: Chr10:77878121-77899456 bp, + strand  Genetic Position: Chr10, 39.72 cM
Alliance:	Dnmt3ltm1Enl page

Germline Transmission:	Earliest citation of germline transmission: J:75938
Parent Cell Line:	J1 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion   Mutation details: An IRES-betageo cassette replaced a genomic fragment containing exons 2-7. Northern blot analysis on targeted ES cells demonstrated that no detectable transcript was expressed from this allele. (J:75938) Inheritance:    Not Specified

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	26 assay results 3 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dnmt3l Mutation:	48 strains or lines available

Original:	J:75938 Hata K, et al., Dnmt3L cooperates with the Dnmt3 family of de novo DNA methyltransferases to establish maternal imprints in mice. Development. 2002 Apr;129(8):1983-93
All:	16 reference(s)