Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Stamtm2Sug
Name:	signal transducing adaptor molecule (SH3 domain and ITAM motif) 1; targeted mutation 2, Kazuo Sugamura
MGI ID:	MGI:2446572
Synonyms:	STAM1flox
Gene:	Stam  Location: Chr2:14078910-14153296 bp, + strand  Genetic Position: Chr2, 10.36 cM, cytoband A2-B
Alliance:	Stamtm2Sug page

Germline Transmission:	Earliest citation of germline transmission: J:80617
Parent Cell Line:	J1 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A region containing exons 3 and 4 was flanked by an upstream single loxP site and a downstream neo cassette immediately followed by a single loxP site. (J:80617)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Stam Mutation:	43 strains or lines available

Original:	J:80617 Yamada M, et al., Signal-Transducing Adaptor Molecules STAM1 and STAM2 Are Required for T-Cell Development and Survival. Mol Cell Biol. 2002 Dec;22(24):8648-58
All:	1 reference(s)