Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Dad1tm1Brw
Name:	defender against cell death 1; targeted mutation 1, Jay L Brewster
MGI ID:	MGI:2445490
Synonyms:	Dad1-Delta1
Gene:	Dad1  Location: Chr14:54472942-54491386 bp, - strand  Genetic Position: Chr14, 27.7 cM
Alliance:	Dad1tm1Brw page

Germline Transmission:	Earliest citation of germline transmission: J:62083
Parent Cell Line:	E14.1 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     Exon 1 was replaced with a neomycin selection cassette inserted by homologous recombination. (J:62083)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dad1 Mutation:	9 strains or lines available

Original:	J:62083 Brewster JL, et al., Deletion of Dad1 in mice induces an apoptosis-associated embryonic death. Genesis. 2000 Apr;26(4):271-8
All:	1 reference(s)