Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Kcnq1ot1tm1.1Mjh
Name:	KCNQ1 overlapping transcript 1; targeted mutation 1.1, Michael J Higgins
MGI ID:	MGI:2429679
Synonyms:	IC2KO, Kcnq1tm1.1Mjh
Gene:	Kcnq1ot1  Location: Chr7:142766848-142850284 bp, - strand  Genetic Position: Chr7, 88.15 cM
Alliance:	Kcnq1ot1tm1.1Mjh page

Germline Transmission:	Earliest citation of germline transmission: J:79882
Parent Cell Line:	J1 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: This allele is derived from Kcnq1tm1Mjh. The floxed PGK-neo cassette that replaced the two floxed CpG islands of intron 10 (KvDMR1) was deleted by crossing mutant animals to the cre deleter strain TgN(Zp3-cre)3Mrt. (J:79882)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

4 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kcnq1ot1 Mutation:	0 strains or lines available

Original:	J:79882 Fitzpatrick GV, et al., Regional loss of imprinting and growth deficiency in mice with a targeted deletion of KvDMR1. Nat Genet. 2002 Nov;32(3):426-31
All:	7 reference(s)