Summary | Mutation origin | Mutation description | Recombinase activity | Find Mice (IMSR) | References

Symbol:	Adgre1tm1(cre)Kpf
Name:	adhesion G protein-coupled receptor E1; targeted mutation 1, Klaus Pfeffer
MGI ID:	MGI:2429642
Synonyms:	F4/80-, F4/80Cre, F4/80-Cre
Gene:	Adgre1  Location: Chr17:57665691-57790527 bp, + strand  Genetic Position: Chr17, 29.8 cM
Alliance:	Adgre1tm1(cre)Kpf page

Germline Transmission:	Earliest citation of germline transmission: J:79911
Parent Cell Line:	E14.1 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Recombinase) Mutations:    Insertion, Intragenic deletion   Adgre1tm1(cre)Kpf expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Adgre1 (MGI:106912)   Mutation details: The insertion of a targeting vector replaced endogenous coding sequence with cre and neo. Northern blot and immunohistochemical analyses indicated the absence of transcript and protein in homozygous mutant mice. Recombination of a floxed reporter verified translation of a functional cre recombinase. (J:79911)

Activity:	Tissue activity of this recombinase allele
Driver:	Adgre1 (mouse) Summary of all recombinase alleles driven by Adgre1. Alliance mouse Adgre1 gene page

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Adgre1 Mutation:	76 strains or lines available

Original:	J:79911 Schaller E, et al., Inactivation of the F4/80 glycoprotein in the mouse germ line. Mol Cell Biol. 2002 Nov;22(22):8035-43
All:	8 reference(s)