Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ephb6tm1Tom
Name:	Eph receptor B6; targeted mutation 1, Toshimitsu Matsui
MGI ID:	MGI:2389310
Gene:	Ephb6  Location: Chr6:41582416-41597443 bp, + strand  Genetic Position: Chr6, 19.77 cM
Alliance:	Ephb6tm1Tom page

Germline Transmission:	Earliest citation of germline transmission: J:79747
Parent Cell Line:	J1 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A portion of exon 1 and all of exons 2 and 3 were replaced by a floxed neo cassette inserted by homologous recombination. The deleted region included the translational start codon. (J:79747)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

2 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ephb6 Mutation:	54 strains or lines available

Original:	J:79747 Shimoyama M, et al., Developmental expression of EphB6 in the thymus: lessons from EphB6 knockout mice. Biochem Biophys Res Commun. 2002 Oct 18;298(1):87
All:	2 reference(s)