Tg(APOE-IL17E)1Mkim
Transgene Detail
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| Symbol: |
Tg(APOE-IL17E)1Mkim |
| Name: |
transgene insertion 1, Mee Rhan Kim |
| MGI ID: |
MGI:2388946 |
| Transgene: |
Tg(APOE-IL17E)1Mkim Location: unknown
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| Alliance: |
Tg(APOE-IL17E)1Mkim page
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(APOE-IL17E)1Mkim expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Homolog in Mouse |
Note |
| human |
IL25 (64806) |
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Mutation details: The transgene consists of a 483 bp full-length human IL17E cDNA, the liver-specific APOE promoter, hepatic control region (HCR), and an SV40 polyadenylation site. Transgene expression was verified by Northern and Western blot analysis of liver extracts from transgenic animals.
(J:79373)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:79373 Kim MR, et al., Transgenic overexpression of human IL-17E results in eosinophilia, B-lymphocyte hyperplasia, and altered antibody production. Blood. 2002 Oct 1;100(7):2330-40 |
| All: |
1 reference(s) |
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