Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Gas1tm1Fan
Name:	growth arrest specific 1; targeted mutation 1, Chen-Ming Fan
MGI ID:	MGI:2388397
Synonyms:	Gas1-
Gene:	Gas1  Location: Chr13:60322219-60325179 bp, - strand  Genetic Position: Chr13, 31.92 cM, cytoband B3-C2
Alliance:	Gas1tm1Fan page

Germline Transmission:	Earliest citation of germline transmission: J:70735
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The entire coding region of the gene was replaced with a PGK-neo cassette via homologous recombination. Absence of gene expression was verified by Western blot analysis of protein extracts from E15 homozygous mutant embryos. (J:70735)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	41 assay results
In Structures Affected by this Mutation:	46 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gas1 Mutation:	14 strains or lines available

Original:	J:70735 Lee CS, et al., Transdifferentiation of the ventral retinal pigmented epithelium to neural retina in the growth arrest specific gene 1 mutant. Dev Biol. 2001 Aug 1;236(1):17-29
All:	9 reference(s)