Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Gjd2tm1Paul
Name:	gap junction protein, delta 2; targeted mutation 1, David L Paul
MGI ID:	MGI:2388383
Synonyms:	Cx36-
Gene:	Gjd2  Location: Chr2:113840082-113844100 bp, - strand  Genetic Position: Chr2, 57.54 cM, cytoband F3
Alliance:	Gjd2tm1Paul page

Germline Transmission:	Earliest citation of germline transmission: J:71117
Parent Cell Line:	J1 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion   Mutation details: The entire coding region was replaced with a lacZ-IRES-ALPP-neo construct via homologous recombination. Absence of gene expression in homozygous mutant animals was verified by immunostaining of frozen retina sections. (J:71117)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gjd2 Mutation:	23 strains or lines available

Original:	J:71117 Deans MR, et al., Synchronous activity of inhibitory networks in neocortex requires electrical synapses containing connexin36. Neuron. 2001 Aug 16;31(3):477-85
All:	61 reference(s)