About   Help   FAQ
Tg(WT1)WANdh
Transgene Detail
Summary
Symbol: Tg(WT1)WANdh
Name: transgene insertion WA, Nicholas D Hastie
MGI ID: MGI:2183654
Synonyms: WT280WA
Transgene: Tg(WT1)WANdh  Location: unknown  
Alliance: Tg(WT1)WANdh page
Transgene
origin
Strain of Origin:  Not Applicable
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(WT1)WANdh expresses 1 gene
 
Mutation detailsA 280 kb YAC containing the human gene WT1 was used as the transgene. Southern blot analysis revealed the loss of upstream and downstream vector arms during YAC integration in founder WA. (J:52756)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Notes
Founders WA and WW carry 1-2 copies of the transgene, and founder WC carries 4-5 copies of the transgene. Founders WC and WW are male sterile.
References
Original:  J:52756 Moore AW, et al., YAC complementation shows a requirement for Wt1 in the development of epicardium, adrenal gland and throughout nephrogenesis. Development. 1999 May;126(9):1845-57
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/25/2025
MGI 6.24
The Jackson Laboratory