Summary | Transgene origin | Transgene description | Expression | Phenotypes | Disease models | Tumor data | Find Mice (IMSR) | Notes | References

Symbol:	Tg(Rbp3-SV40)IT-2Jjw
Name:	transgene insertion IT-2, Jolene J Windle
MGI ID:	MGI:2385652
Synonyms:	IRBP-Tag
Transgene:	Tg(Rbp3-SV40)IT-2Jjw  Location: unknown
Alliance:	Tg(Rbp3-SV40)IT-2Jjw page

Strain of Origin:

(BALB/cAnNHsd x C57BL/6NHsd)F2

Transgene Type:    Transgenic (Inserted expressed sequence) Mutation:    Insertion   Mutation details: 2.7 kb of the SV40 T antigen gene fused to 1.9 kb of mouse RBP3 promoter sequences was used as the transgene. Promoter sequences from -1783 to +101 were used to drive expression of the transgene in photoreceptor cells. Northern blot analysis confirmed transgene expression in the retina and pineal of transgenic animals. (J:60231)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

3 anatomical structure(s)

List all tumor models in MMHCdb carrying Tg(Rbp3-SV40)IT-2Jjw

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:60231 Howes KA, et al., Photoreceptor cell tumors in transgenic mice. Invest Ophthalmol Vis Sci. 1994 Feb;35(2):342-51
All:	3 reference(s)