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Tg(Prnp)1Co
Transgene Detail
Summary
Symbol: Tg(Prnp)1Co
Name: transgene insertion 1, George A Carlson
MGI ID: MGI:2387684
Transgene: Tg(Prnp)1Co  Location: unknown  
Alliance: Tg(Prnp)1Co page
Transgene
origin
Strain of Origin:  (C57BL/6 x SJL)F1
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Prnp)1Co expresses 1 gene
 
Mutation detailsCosmid clone cos.6I/LnJ-4 carrying mouse gene Prnp was used for the transgene. The cosmid Prnp sequence is derived from inbred strain I/LnJ, which carries the Prnpb allele (valine residue at position 189). Expression of the transgene was verified by RT-PCR analysis of transgenic animals. (J:11316)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:11316 Westaway D, et al., Paradoxical shortening of scrapie incubation times by expression of prion protein transgenes derived from long incubation period mice. Neuron. 1991 Jul;7(1):59-68
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory