Tg(MMTV-Fgf3)NR1Mul
Transgene Detail
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Symbol: |
Tg(MMTV-Fgf3)NR1Mul |
Name: |
transgene insertion NR1, William Muller |
MGI ID: |
MGI:2388025 |
Synonyms: |
int-2, TG.NR |
Transgene: |
Tg(MMTV-Fgf3)NR1Mul Location: unknown
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Alliance: |
Tg(MMTV-Fgf3)NR1Mul page
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Transgene Type: |
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Transgenic (Inserted expressed sequence) |
Mutation: |
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Insertion
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Tg(MMTV-Fgf3)NR1Mul expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Note |
mouse |
Fgf3 (MGI:95517) |
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Mutation details: A mouse Fgf3 cDNA fused to a shortened MMTV promoter was used as the transgene. The MMTV promoter deleted 5' to the Cla1 site directs transgene expression in mammary glands. High levels of transgene expression were observed in mammary glands and prostate. A low level of transgene expression was also observedin salivary glands of male and female transgenic animals.Transgene expression in mammary glands was verified by RNase protection assay.
(J:71557)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:71557 Muller WJ, et al., The int-2 gene product acts as an epithelial growth factor in transgenic mice. EMBO J. 1990 Mar;9(3):907-13 |
All: |
4 reference(s) |
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