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Tg(MMTV-Fgf3)NR1Mul
Transgene Detail
Summary
Symbol: Tg(MMTV-Fgf3)NR1Mul
Name: transgene insertion NR1, William Muller
MGI ID: MGI:2388025
Synonyms: int-2, TG.NR
Transgene: Tg(MMTV-Fgf3)NR1Mul  Location: unknown  
Alliance: Tg(MMTV-Fgf3)NR1Mul page
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(MMTV-Fgf3)NR1Mul expresses 1 gene
 
Mutation detailsA mouse Fgf3 cDNA fused to a shortened MMTV promoter was used as the transgene. The MMTV promoter deleted 5' to the Cla1 site directs transgene expression in mammary glands. High levels of transgene expression were observed in mammary glands and prostate. A low level of transgene expression was also observedin salivary glands of male and female transgenic animals.Transgene expression in mammary glands was verified by RNase protection assay. (J:71557)
Tumor Data
List all tumor models in MMHCdb carrying Tg(MMTV-Fgf3)NR1Mul
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:71557 Muller WJ, et al., The int-2 gene product acts as an epithelial growth factor in transgenic mice. EMBO J. 1990 Mar;9(3):907-13
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory