Tg(Ckmm-Dmd)3Chmb
Transgene Detail
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| Symbol: |
Tg(Ckmm-Dmd)3Chmb |
| Name: |
transgene insertion 3, Jeffrey S Chamberlain |
| MGI ID: |
MGI:2387942 |
| Synonyms: |
delta1-62 |
| Transgene: |
Tg(Ckmm-Dmd)3Chmb Location: unknown
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| Alliance: |
Tg(Ckmm-Dmd)3Chmb page
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(Ckmm-Dmd)3Chmb expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Note |
| mouse |
Dmd (MGI:94909) |
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Mutation details: The transgene is composed of Dmd cDNA sequences from exon 1 and exons 63-79 which encode the C-terminus of the full-length protein. The transgene is fused to mouse the Ckmm promoter/enhancer, exon 1, intron 1, and part of exon 2, which drives espression in skeletal muscle. Specific expression of the transgene in skeletal and cardiac tissue of transgenic animals was confirmed by Western blot analysis.
(J:21841)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:21841 Cox GA, et al., Dp71 can restore the dystrophin-associated glycoprotein complex in muscle but fails to prevent dystrophy [see comments]. Nat Genet. 1994 Dec;8(4):333-9 |
| All: |
4 reference(s) |
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Analysis Tools
