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Tg(Alb1-NR1I2)1Rev
Transgene Detail
Summary
Symbol: Tg(Alb1-NR1I2)1Rev
Name: transgene insertion 1, Ronald M Evans
MGI ID: MGI:2386090
Synonyms: Alb-SXR, hPXR
Transgene: Tg(Alb1-NR1I2)1Rev  Location: unknown  
Alliance: Tg(Alb1-NR1I2)1Rev page
Transgene
origin
Strain of Origin:  (BALB/c x C57BL/6)F1
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Alb1-NR1I2)1Rev expresses 1 gene
 
Mutation detailsHuman NR1I2 cDNA fused to a mouse liver-specific albumin promoter was used as the transgene. Expression of the human transgene was verified by Northern blot analysis of liver tissue from transgenic animals. (J:63639)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:63639 Xie W, et al., Humanized xenobiotic response in mice expressing nuclear receptor SXR. Nature. 2000 Jul 27;406(6794):435-9
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/09/2025
MGI 6.24
The Jackson Laboratory